May 7, 2025
Severe Allergic Reactions at Work
By Safety Team
Prepare your team to recognize and respond to anaphylaxis in the workplace, where minutes of delay can mean the difference between recovery and death.
emergency-responseShareable Safety Snapshot
Severe Allergic Reactions at Work
Prepare your team to recognize and respond to anaphylaxis in the workplace, where minutes of delay can mean the difference between recovery and death.
If a coworker you had never spoken to about allergies suddenly went into anaphylaxis in front of you, would you know where to find epinephrine -- and if not, what system should exist so that information is immediately available?
What is the difference between an allergic reaction that will resolve on its own and one that will kill someone in minutes, and how does that uncertainty affect your willingness to administer epinephrine?
Should workplaces stock unassigned epinephrine auto-injectors the way they stock AEDs -- for anyone who needs them, prescribed or not -- and what are the arguments for and against that policy?
What is Severe Allergic Reactions at Work?
Warehouse associate Tanya Blevins was stung by a yellow jacket while moving pallets in an outdoor staging area at a distribution center in Indianapolis. Within three minutes, her face swelled dramatically, she developed full-body hives, and she told a coworker she felt like her throat was closing. Tanya carried an epinephrine auto-injector in her locker -- 150 feet away -- but her hands were shaking too badly to retrieve it herself. A coworker who had never used an auto-injector hesitated for nearly two minutes before running to the locker, reading the instructions, and administering the injection. Tanya survived, but the allergist later told her that the two-minute delay brought her dangerously close to respiratory arrest.
Severe allergic reactions at work -- specifically anaphylaxis -- are rapid-onset, life-threatening immune responses triggered by insect stings, foods, latex, medications, or chemical exposures encountered in the workplace. Preparation means knowing who on your team has known allergies, where their medication is stored, how to administer it, and how to act without hesitation when seconds determine the outcome.
Key Components
1. Common Workplace Allergen Triggers
- Insect stings from bees, wasps, yellow jackets, and fire ants are the leading cause of workplace anaphylaxis, particularly in outdoor, agricultural, landscaping, and construction environments
- Latex gloves and latex-containing equipment trigger reactions in an estimated 1 to 6 percent of the general population, with higher rates among healthcare and laboratory workers with repeated exposure
- Chemical sensitizers including isocyanates in spray paints, formaldehyde in adhesives, and certain cleaning products can cause severe respiratory allergic reactions after repeated workplace exposure
- Food allergens in shared break rooms, catered events, and vending machines present risks that are often overlooked because people do not associate eating at work with occupational hazards
2. Recognizing Anaphylaxis and Acting Immediately
- Anaphylaxis typically involves two or more body systems simultaneously: skin reactions like hives and swelling, respiratory symptoms like wheezing and throat tightness, cardiovascular symptoms like rapid pulse and dizziness, and gastrointestinal symptoms like nausea and vomiting
- The single most important action is administering epinephrine immediately -- do not wait to see if symptoms improve, do not substitute antihistamines, and do not hesitate because you are unsure
- Administer the auto-injector by pressing it firmly into the outer thigh, which can be done through clothing, holding for 10 seconds, and then calling 911 immediately
- Position the person lying on their back with legs elevated to maintain blood pressure, unless they are vomiting or having difficulty breathing in which case keep them seated upright
3. Workplace Preparedness and Emergency Planning
- Maintain a voluntary allergen awareness registry so supervisors and team leads know which employees have severe allergies and where their emergency medications are stored
- Keep epinephrine auto-injectors in accessible, clearly marked locations rather than locked in personal lockers where the allergic individual may not be able to reach them during a reaction
- Train all team members -- not just designated first aiders -- on epinephrine auto-injector use, because the designated responder may not be present when anaphylaxis occurs
- Develop site-specific emergency action plans for anaphylaxis that include the location of epinephrine, the nearest hospital with emergency capabilities, and the expected EMS response time
Building Your Safety Mindset
Know Your Team's Allergy Risks
- During your next team meeting, ask if anyone has a severe allergy and would like to share their emergency action plan -- create a safe space for disclosure without pressure
- Learn the specific triggers for each allergic individual on your team so you can help avoid exposure and respond appropriately if a reaction occurs
- Understand that a person can develop a new severe allergy at any age with no prior history, so even someone who has been stung or exposed before without reaction can suddenly experience anaphylaxis
Eliminate Hesitation Through Practice
- Handle an epinephrine auto-injector trainer device so you know the weight, the grip, and the motion required to deploy it against someone's thigh without fumbling
- Repeat the sequence out loud until it is automatic: recognize the reaction, retrieve the epinephrine, inject the thigh, call 911, monitor and comfort
- Accept that using epinephrine on someone experiencing anaphylaxis cannot cause harm -- the risk of not giving it is death, and the risk of giving it unnecessarily is a temporary increase in heart rate
Create an Environment That Reduces Exposure
- Inspect outdoor work areas for insect nests before beginning work, especially in spring and summer when stinging insect activity peaks
- Transition from latex to nitrile gloves in all work areas to eliminate a common allergen without sacrificing hand protection
- Ensure that chemical safety data sheets are reviewed for sensitization potential before introducing new products to the workplace
Discussion Points
- If a coworker you had never spoken to about allergies suddenly went into anaphylaxis in front of you, would you know where to find epinephrine -- and if not, what system should exist so that information is immediately available?
- What is the difference between an allergic reaction that will resolve on its own and one that will kill someone in minutes, and how does that uncertainty affect your willingness to administer epinephrine?
- Should workplaces stock unassigned epinephrine auto-injectors the way they stock AEDs -- for anyone who needs them, prescribed or not -- and what are the arguments for and against that policy?
Action Steps
- Ask your supervisor whether anyone on your team has a known severe allergy and confirm that their emergency medication is accessible and not expired
- Practice the epinephrine auto-injector administration sequence using a trainer device or by reviewing the printed instructions on an actual auto-injector without removing the safety cap
- Inspect your work area for stinging insect nests, latex products, and chemical sensitizers that could trigger severe allergic reactions, and report findings to your safety coordinator
- Verify that your site's emergency action plan includes a specific protocol for anaphylaxis, including epinephrine locations and the nearest hospital capable of managing severe allergic reactions